每日医学AI论文简报（摘要版）
[日报]日期: 2026-07-26 07:05 来源: PubMed | 分析: DeepSeek（摘要级） 说明: 当日通过相关度过滤的论文没有 PMC 全文，v0.3 管线降级生成本摘要版简报。
1. Human-AI co-design for clinical prediction models.
NPJ digital medicine | 2026 | PubMed ⚠️ | DOI
摘要: Developing safe, effective, and practically useful clinical prediction models (CPMs) traditionally requires extensive collaboration between clinical experts, data scientists, and informaticists to refine the many small but critical details of the model building process. When incorporating unstructured clinical notes, this challenge magnifies, as notes essentially contain an infinite number of concepts that can be used for modeling. We introduce HACHI, an iterative human-in-the-loop framework that uses AI agents to accelerate the development of fully interpretable CPMs from clinical notes, where CPMs are defined as linear models of yes-no questions. HACHI alternates between an AI agent that uses statistical tools and embedded knowledge to explore candidate concepts and domain experts who provide feedback to the AI agent. The framework optimizes for transparency, steerability, and reciproc