全部论文（83 篇）
Navigating regulatory fragmentation in the convergence of synthetic biology, artificial intelligence, and automation. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Short-term BMI changes associated with self-selected weight-control dietary patterns among Chinese office-based adults using a digital health platform: An exploratory real-world observational study. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
GRAF1-dependent endocytotic processes and the Golgi apparatus contribute to previously unrecognized intermediate stages of early ciliogenesis. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Associations between diet quality, epigenetic aging and epigenome in two population-based cohorts. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
When documentation follows the patient: Unprofessional language and behavioral health referrals in substance use disorder - a retrospective cohort study using LLM-augmented natural language processing. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Healthcare professionals' intention to adopt a smart diabetic foot screening system: A UTAUT-informed mixed-methods study. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Artificial intelligence for healthcare in Nepal: A scoping review of clinical applications, implementation evidence, and health-system governance. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Cavity-enhanced optical readout and control of nuclear spin qubits. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Spatial lipidomics of the human brain: systematic review of current state and future perspectives. 🆕
2026-08-31 ·
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Time-dependent prognostic value of coronary plaque burden and hyperemic myocardial blood flow. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Universal pipeline for high-resolution GPCR structure determination. 🆕
2026-08-31 ·
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
CSF p-tau205: a biomarker of Alzheimer's disease progression and biological staging. 🆕
2026-08-31 ·
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Causal Endotype-Based Classification of Myocardial Infarction. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Trends and hotspots in artificial intelligence applications for atherosclerosis research: A bibliometric analysis. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Protein-protein interaction network architecture of human polygenic traits reveals domain-spanning connectivity and evolutionary pressures. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Stroke risk in younger age groups is increasing and requires targeted prevention. 🔄
2026-09-01 ·
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Genetic frontotemporal degeneration across the lifespan? A critical appraisal of the neurodevelopmental hypothesis. 🆕
2026-09-01 ·
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Evaluating foundation models on official German medical licensing examinations: Implications for high-stakes assessment and AI-assisted medical education. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
The changing surface of the world's roads. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Design and multidimensional expert evaluation of a national health information portal-integrated generative AI chatbot for health literacy and awareness. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Promiscuous RNA binding by WDR5 remodels the KMT2A (MLL1) histone methyltransferase complex to an inactive state. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
A targeted behavioral economics-based mobile health intervention to improve medication adherence in patients with hypertension: A three-arm randomized controlled trial. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Spatial mapping of RNA turnover kinetics in the mouse brain. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Short-term effects of combinations of heart failure therapies on blood pressure, kidney function and serum potassium. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
How telemonitoring impacts the responsibilities of patients and healthcare professionals in cardiology: A Q-methodology study. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Pathogenic tau in the mouse locus coeruleus produces noradrenergic hyperactivity and neuropsychiatric phenotypes reminiscent of early Alzheimer's disease. 🔄
2026-09-03 ·
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Nutraceuticals and phytoceuticals for the treatment of major depressive disorder: a systematic review and network meta-analysis. 🔄
2026-09-03 ·
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Bias in administrative coding for mitral valve prolapse: Implications for electronic health record research. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
OmicsPred as a centralized resource for genetic prediction of multi-omic traits. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
A single-cell atlas of multiple myeloma defines malignant archetypes and proliferative states. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Monocyte-derived galectin-1(hi) cells provide innate immune help in the generation of functional memory CD8(+) T cells. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
State-dependent signal flow hierarchy in the human cerebral cortex. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Developmental deviations of association-network structural connectivity in youths with ADHD predict symptom and treatment outcomes. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Isthmin-2 is a first-trimester predictor of preeclampsia and fetal growth restriction. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Atezolizumab in early triple-negative breast cancer: the randomized phase 3 NSABP B-59/GeparDouze trial. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Serial Ketamine Infusions for Treatment-Resistant Bipolar Depression: A Randomized Clinical Trial. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Long-Term Outcomes Following Bilateral vs Single Internal Thoracic Artery Grafts: A Secondary Analysis of a Randomized Clinical Trial. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Workload and Perceived Burden From a National Survey of Surgeons. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Extracorporeal CO(2) elimination for acute exacerbation of severe COPD requiring invasive mechanical ventilation: a randomized controlled trial (the X-COPD trial). 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Structured experience shapes strategy learning and neural dynamics in the medial entorhinal cortex. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Death determination at the bedside: clinical judgement beyond criteria. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Healthcare professionals' readiness and perceived barriers to drone-assisted emergency healthcare in Palestine. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Guanosine 10 methylation by TRMT11-TRMT112 optimizes human mitochondrial tRNAs for efficient translation. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
All-optical multimodal mapping of single-cell-type-specific metabolic activities via REDCAT. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
YTHDF1 modulates CAP1-mediated actin turnover to regulate synaptic function and anxiodepressive-like behaviors. 🆕
2026-09-05 ·
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Target site selection and P1 engineering enable highly efficient circular RNA production via end-to-end self-targeting and splicing. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Zipper polydefluorination-monoborylation of perfluoroalkyl chains. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Open-source versus proprietary large language models for academic writing in medicine: A controlled evaluation of DeepSeek-R1 and ChatGPT-o1 in neuroradiology. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Structures and dynamics of the major G-quadruplex in the human PDGFR-β gene promoter: insights into vacancy G-quadruplex formation. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Effect of human urinary microenvironment and fluid flow on antibiotic and phage therapy efficacy against uropathogenic Escherichia coli. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Coherent terahertz magnon-phonon three-wave mixing in a layered antiferromagnet. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Navigating the base excision repair pathway in chromatin-focus on oxidative DNA damage. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Spatial isoform sequencing at single-cell resolution reveals cell-type-specific spatial isoform variability in multiple brain cell types. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
A five-phase evaluation framework for diagnostic and predictive medical artificial intelligence. 🆕
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Risks of adverse respiratory outcomes in adults with cancer over the course of survivorship compared with cancer-free individuals: a matched cohort study using linked English electronic health records. 🔄
2026-09-06 ·
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
State-Level Abortion Policies and Infant Health Outcomes. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Social Media Use Among People Living with Chronic Pain: Cross-Sectional Study of Associated Factors. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Mapping the landscape of MRI research in post-stroke cognitive impairment: A bibliometric analysis from 2000 to 2026. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Genetic Testing Uptake Among Patients With Newly Diagnosed Breast Cancer. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Calcium silicate-diorthocarbonate is a missing link in deep-mantle chemistry of silicates and carbonates. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Ternary Neurexin-T178-PTPR complexes represent a pre-synaptic core-module of neuronal synapse organization. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Prevalence of Use of Mobile Food Delivery Services During School Hours in the United States: Survey Study. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Web-Based, Open-Source LGBTQ+ Affirming Care Education for Primary Health Care Providers: Descriptive Analysis. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Risk of bone metastases on [(18)F]NaF PET/CT in 734 patients with newly diagnosed prostate cancer. 🔄
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
The underappreciated role of rifampin in shaping the epidemiology of RT027-like Clostridioides difficile lineages. 🔄
2026-09-06 ·
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Transforming large language models into medical specialists via knowledge injection.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Daraxonrasib for Previously Treated RAS-Mutant Non-Small-Cell Lung Cancer.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
AI-Empowered Nuclear Medicine Education, Part 1: Theoretical and Ethical Foundation.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Evaluating large language models for structuring cardiology reports: a real-world clinical study on patient subtyping and trial recruitment.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Quality and safety of large language model generated communication in psychodermatology: a bilingual scenario-based evaluation.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Prototype-guided Multimodal Retrieval for Knowledge-assisted Interventional Radiology.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
uPAR exhibits age- and region-dependent expression in the brains of mice with Alzheimer's disease-like pathology.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
LLMs as Clinical Instruments-Toward Verifiable Reasoning.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Agentic AI for Spatial Omics.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Adversarial and Correlation-Aware Data Augmentation Framework for Multi-Label Chest X-Ray Image Classification.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Embracing intra-class heterogeneity for semi-supervised medical image segmentation: From diversity to precision.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
ACEA-Net: Weakly Supervised Prostate 3D MRI Image Segmentation via Advanced Prompt Points.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Retrieval-Augmented Representation for Semi-Supervised Medical Image Segmentation.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Leveraging modality-guided pre-training for dual-prompt-driven multi-cancer PET-CT segmentation.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Adapting pathology foundation models for continual cross-center WSI retrieval.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。
Targeting claudins in cancer.
类型：综述（Review article）
领域：肿瘤学；药物发现；紧密连接与claudin家族；靶向治疗；细胞屏障与旁细胞转运。
方法：叙述性综述。综合细胞/动物模型、人类遗传病、临床前与临床药物开发证据；补充材料以表格汇总Cldn缺陷小鼠异常表型和人类CLDN突变相关疾病，并附参考文献。
一句话：该综述系统梳理claudin家族在生理、遗传病和癌症中的作用，并讨论将其作为癌症靶点的治疗机遇与安全性挑战。
ContiMorph: An unsupervised learning framework for cardiac motion tracking with time-continuous diffeomorphism.
本期未做逐篇深度分析，当前为 PubMed 元数据；可后台补跑 DeepSeek 逐篇分析后自动补全。